Erlangen 2018 – wissenschaftliches Programm
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Q: Fachverband Quantenoptik und Photonik
Q 65: Nano-Optics and Biophotonics
Q 65.7: Vortrag
Freitag, 9. März 2018, 12:00–12:15, K 0.023
Femtosecond 3D printing of an entire mini-microscope for neurobiological applications — •Chenyang Zhang1, Simon Thiele2, Simon Ristok1, Ksenia Weber1, Alois Herkommer2, and Harald Giessen1 — 14th Physics Institute and Research Center SCoPE, University of Stuttgart, Pfaffenwaldring 57, 70569 Stuttgart, Germany — 2Institute of Technical Optics and Research Center SCoPE, University of Stuttgart, Pfaffenwaldring 9, 70569 Stuttgart, Germany
Using genetically modified mice, it is possible to observe the calcium ion transport in their brain cells. Green fluorescent protein with a peak luminescence at 510 nm indicates where the electric signals in the brain of mice flow after particular stimuli. Currently, a miniature microscope of the size in the range of centimeters is glued to the opened skull of the living mice. This allows for monitoring their thoughts. However, the size and weight of this microscope is hampering their motion and agility. Here, we demonstrate a 3D printed microscope imaging system including blue fluorescence excitation which allows for decent magnification and subsequent imaging. We utilize a femtosecond laser for printing. The size of the microscope is as small as a few mm, thus reducing the volume and the weight significantly.