Würzburg 2018 – scientific programme

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ST: Fachverband Strahlen- und Medizinphysik

ST 5: Biomedical Imaging II

ST 5.3: Talk

Wednesday, March 21, 2018, 17:00–17:15, Phys-HS P

Quantitative single-shot phase-contrast radiography at synchrotrons: A comparison between propagation-based and grating-based imaging on the basis of simulated data — •Max Schuster, Maria Seifert, Andreas Wolf, Thilo Michel, Gisela Anton, and Stefan Funk — ECAP - Erlangen Centre for Astroparticle Physics, Universität Erlangen-Nürnberg, Erwin-Rommel-Str. 1, 91058 Erlangen

Both, propagation- and grating-based X-ray phase contrast imaging (pbPCI & gbPCI) enable the retrieval of the phaseshift imprinted on an X-ray wave by the interaction with matter. This offers sensitivity to local variations in the electron density distribution and thus provides improved contrast for soft tissue imaging. pbPCI is a well-established method for high spatial resolution measurements at synchrotron beamlines [1,2]. Single-shot pbPCI additionally enables measurements at high temporal resolution. This is of special interest for time-resolved measurements, e.g. studies of dynamic bio-medical processes at synchrotrons [1,3]. In the case of gbPCI, single-shot acquisition can be realized by means of Fourier imaging [4]. Here, a comparison of both techniques with regard to their imaging potential, in particular their capabilities to resolve overlapping structures as they appear in complex objects, is drawn on the basis of simulated data for a synchrotron scenario. [1] Kitchen, M. J., et al. Phys. Med. Biol. 60.18 (2015): 7259. [2] Baran, P., et al. Phys. Med. Biol. 62.6 (2017): 2315. [3] Lewis, R. A., et al. Phys. Med. Biol. 50.21 (2005): 5031. [4] Takeda, M., et al. JosA 72.1 (1982): 156-160.