München 2019 – wissenschaftliches Programm

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SYPP: Symposium Pulsed Power für Medizin und Biotechnologie

SYPP 2: Pulsed Power für Medizin und Biotechnologie II

SYPP 2.3: Hauptvortrag

Donnerstag, 21. März 2019, 15:00–15:30, HS 3

Pulse Generators for a Scale-Up of an Electroporation Device for Mash — •Martin Sack¹, Martin Kern², Hermann Armbruster³, Johannes Fleig¹, Dennis Herzog¹, Martin Hochberg¹, and Georg Mueller¹ — ¹Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany — ²KEA-TEC GmbH, Kaigartenallee 8, 68753 Waghäusel, Germany — ³Armbruster Kelterei-Technologie GmbH, Zu den Weiherwiesen 1-3, 74363 Güglingen, Germany

For a scale-up of an electroporation device for mash an existing design for a Marx generator equipped with spark gap switches has been improved to allow for a higher pulse repetition rate and a synchronized operation of two Marx generators charged by a single high-voltage power supply. As the pulse repetition rate of spark gap switches is limited due to the time required to remove charged particles and debris from the inter-electrode area, each spark gap has been equipped with a nozzle to guide the gas towards the gap and, hence, increase the gas flow between the electrodes. A pulse repetition rate of 38 Hz has been achieved. Synchronized operation of Marx generators feeding one electroporation chamber enables to overcome limitations in power due to the circuit inductance. A trigger circuit to trigger the generators by overvolting the first spark gap has been set up and tested successfully. In the talk selected design details and results will be presented.