Regensburg 2019 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 12: Poster II

BP 12.36: Poster

Dienstag, 2. April 2019, 14:00–16:00, Poster B2

Effect of reactive oxygen and nitrogen species on lipid monolayers — •Florian Gellert, Heiko Ahrens, Renko Kensbock, and Christiane A. Helm — Institute of Physics, University of Greifswald, 17489 Greifswald

Oxidative degeneration of lipids can lead to severe damages of the biological cell membrane. The phenomenon is initiated by reactive radicals, such as certain reactive oxygen/nitrogen species (ROS/ RNS). To investigate this behaviour, we use monolayers at the air/ water interface of unsaturated lipids as model membranes. Self-assembling- and phase transition behaviour of monolayers in a Langmuir-Blodgett trough are studied by isotherms. Domain formation is studied by video-speed Brewster angle microscopy. The reactive species are formed either by a low temperature plasma jet (kINPen) or are dissolved in the subphase at low concentrations. Thus, we address the question whether the ROS/ RNS attacks the unsaturated alkyl chains or the head group of the lipid.