Regensburg 2019 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 12: Poster II
BP 12.43: Poster
Dienstag, 2. April 2019, 14:00–16:00, Poster B2
Study of the Structure and Kinetic of Photoswitchable Lipid Monolayers Influenced by Different Sugar Groups — •Svenja Carolin Hövelmann1, Jonas Erik Warias1, Alexander Hebel1, Franziska Reise3, Thisbe Lindhorst3, Olaf Magnus Magnussen1, and Bridget Mary Murphy1,2 — 1Institut für Experimentelle und Angewandte Physik, University of Kiel, Germany — 2Ruprecht Haensel Laboratory, University of Kiel, Germany — 3Otto Diels-Institut für Organische Chemie, University of Kiel, Germany
The phospholipid membranes with their mechanical and dynamical properties have an important role in biological functions. To study these properties we us a model system of a Langmuir film of amphiphilic phospholipids with embedded photoswitchable molecules. These molecules are glycolipids containing an azobenzene photoswitch between the chain and the head group and are embedded in a monolayer of dipalmitoylphosphatidylcholine (DPPC). In order to investigate the influence of a different number of sugar groups attached to the molecules multiple molecules are prepared. Langmuir isotherms and X-ray reflectivity are used to study the structural differences between the molecules and the structural changes when illuminated as the orientation of the azobenzene-glycolipid switches reversibly between trans- and cis-conformation by illumination of UV and blue light. Differences between the molecules in terms of their switching behaviour and membrane conformations can be observed.