Regensburg 2019 – scientific programme
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BP: Fachverband Biologische Physik
BP 12: Poster II
BP 12.45: Poster
Tuesday, April 2, 2019, 14:00–16:00, Poster B2
Limiting shapes of confined lipid vesicles — •Bor Kavčič1, Ai Sakashita2,3, Hiroshi Noguchi3, and Primož Ziherl4,5 — 1IST Austria, Klosterneuburg, Austria — 2Ochanomizu University, Tokyo, Japan — 3University of Tokyo, Tokyo, Japan — 4University of Ljubljana, Ljubljana, Slovenia — 5Jožef Stefan Institute, Ljubljana, Slovenia
We theoretically study the shapes of lipid vesicles confined to a spherical cavity, elaborating a framework based on the so-called limiting shapes constructed from geometrically simple structural elements such as double-membrane walls and edges. Partly inspired by numerical results, the proposed non-compartmentalized and compartmentalized limiting shapes are arranged in the bilayer-couple phase diagram which is then compared to its free-vesicle counterpart. We also compute the area-difference-elasticity phase diagram of the limiting shapes and we use it to interpret shape transitions experimentally observed in vesicles confined within another vesicle. The limiting-shape framework may be generalized to theoretically investigate the structure of certain cell organelles such as the mitochondrion.