Regensburg 2019 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 12: Poster II
BP 12.49: Poster
Dienstag, 2. April 2019, 14:00–16:00, Poster B2
Spike Termination in Networks of Bistable Neurons — •Muhammet Uzuntarla1, Joaquin J. Torres2, Ali Calim1, and Ernest Barreto3 — 1Department of Biomedical Engineering, Bulent Ecevit University, Turkey — 2Department of Electromagnetism and Physics of the Matter, University of Granada, Spain — 3Department of Physics and Astronomy, George Mason University, USA
In neural systems, synchronization is widely considered to be responsible for the origin of oscillatory brain rhythms. Findings from experimental and theoretical studies suggest that it results from interplay between intrinsic properties of individual neurons, synaptic interaction dynamics and topological features. An interesting synchronization-induced emergent behavior is termination of ongoing population activity. We observe and study this phenomenon whereby neural activity spontaneously ceases. Here, we investigate the behavior of three types of networks composed of bistable HH neurons with a scale-free topology, involving either electrical or chemical synapses that are either excitatory or inhibitory. We find that periodic synchronous population activity emerges in all three networks, and strongly synchronized population spiking events lead to complete cessation of activity in excitatory networks, but not in gap junction or inhibitory networks. We identify the underlying mechanism responsible for this phenomenon by examining the particular shape of excitatory postsynaptic currents. We also examine the effects of the synaptic time constant, coupling strength, and channel noise on the occurrence of the phenomenon.