Regensburg 2019 – scientific programme

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BP: Fachverband Biologische Physik

BP 12: Poster II

BP 12.8: Poster

Tuesday, April 2, 2019, 14:00–16:00, Poster B2

Developing a fast microrheological sensor device with live tracking — •Jonas Pfeil, Daniel Geiger, Tobias Neckernuss, and Othmar Marti — Institute of Experimental Physics, Ulm University, Ulm, Germany

Passive microrheology (PMR) based on tracking of incorporated coated polystyrene beads is an established technique to measure physical properties of biological tissue. PMR works by imaging the beads at very high frame rates in the kHz range and observe the brownian motion with sub-pixel resolution. From this motion the rheological properties of the tissue are computed. Some of the issues are the high speed imaging requirements and the needed tracking to calculate the information. We present a new device consisting of an image sensor and a field programmable gate array (FPGA) to lower the bandwidth requirements of the sensor and to track the beads in real time. This drastically reduces the storage requirements and bandwidth needed for the measurement, allowing very long duration, continuous measurements with cost efficient hardware.