Regensburg 2019 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 24: Cell adhesion and migration, multicellular systems I

BP 24.1: Hauptvortrag

Donnerstag, 4. April 2019, 09:30–10:00, H11

Active motion in living systems: from molecules to assemblies of organisms — •Ben Fabry — Department of Physics, University of Erlangen-Nuremberg, Erlangen, Germany

The dynamics of active motion in living system is governed by intermittency and approach to kinetic arrest in striking analogy with inert non-equilibrium systems, including soft glasses and jammed colloidal assemblies. The emerging collective behavior of active agents, from molecules, cells, groups of cells up to the level of individual organisms, appears to depend on the shape and magnitude of the interaction potential between the agents and on the distance of the system's effective temperature from a critical point. These well-established concepts in condensed matter physics link dynamic interactions between the underlying elements to integrative biological functions at the macroscale, such as cytoskeletal arrangements at the leading edge of migrating cells, heterogeneity of immune cell migration, collective matrix invasion in metastasizing cancer cell assemblies, and the organization of penguin colonies.