Regensburg 2019 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 33: Closing talk (joint session BP/CPP/DY)

BP 33.1: Hauptvortrag

Freitag, 5. April 2019, 12:30–13:15, H1

Pattern formation in active cytoskeletal systems — •Andreas R. Bausch — Lehrstuhl für Biophysik, Technische Universität München, 85747 Garching

Living cells rely on the self-organization mechanisms of cytoskeleton to adapt to their requirements. In processes such as cell division, or cellular motility rely on the controlled self-assembly and disassembly of well defined active cytoskeletal structures interacting with lipid membranes. One important and promising strategy to identify the underlying governing principles is to quantify the underlying physical processes in model systems mimicking functional units of living cell. Here I*ll present in vitro minimal model systems consisting of active microtubule and actin filament systems which show pattern formation resulting from active transport processes. I will discuss how small variations in local interactions results in nematic or polar patterns in high density motility essays. With the example of reconstituted active vesicles I will discuss how to relate local force exertion and tension generation to shape transformations, blebbing, invagination or tethering of lipid membranes