Regensburg 2019 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 6: Poster I
BP 6.66: Poster
Montag, 1. April 2019, 17:30–19:30, Poster B2
Multi-scale microrheology using fluctuating semiflexible filaments as stealth probes — •Kengo Nishi1, Fred MacKintosh2, and Christoph Schmidt1,3 — 1University of Goettingen, Goettingen, Germany — 2Rice University, Houston, USA — 3Duke University, Durham, USA
Microrheology is commonly performed using micron-sized beads embedded in the (soft)medium to be studied. Inserting beads can be problematic in confined or hard to access places and can cause artefacts. Here, we introduce the use of single-walled carbon nanotubes (SWNTs), which are model semi-flexible polymers with non-photobleaching fluorescence, as stealth probes. We embedded SWNTs in viscoelastic media and analyzed thermally driven shape fluctuations. We show that the bending dynamics of SWNTs embedded in soft media can be used to probe the viscoelastic properties of such media at multiple scales, corresponding to the wavelengths of the modes analyzed. We found that the viscoelastic moduli of polymer solutions measured by SWNTs are in excellent agreement with those by measured by conventional micro/macrorheology, which validates the method.