Regensburg 2019 – scientific programme

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 18: Crystallization, Nucleation and Self-Assembly II (joint session CPP/BP)

CPP 18.2: Talk

Tuesday, April 2, 2019, 09:45–10:00, H14

Protein crystallization near liquid-liquid phase separation — Klim Petrov, Jan Hansen, •Florian Platten, and Stefan U. Egelhaaf — Heinrich Heine University Duesseldorf

The crystallization of protein (lysozyme) solutions is studied as a function of protein and salt concentration at ambient conditions. In addition to tetragonal crystals at low salt concentrations (far away from phase separation), needle-like and kinetically roughened crystals occur in the vicinity of the binodal. The crystallization induction time and the growth rate are inferred from optical microscopy and linked to the solubility and protein-protein interactions. Based on these data, the different states of the protein solution are linked to different driving forces for crystallization.