Regensburg 2019 – wissenschaftliches Programm
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ST: Fachverband Strahlen- und Medizinphysik
ST 1: X-ray Imaging
ST 1.2: Vortrag
Montag, 1. April 2019, 15:15–15:30, H48
Dose-compatible grating-based phase-contrast mammography on mastectomy specimens using a compact synchrotron source — Elena Eggl1,2, •Lisa Heck1,2,3, Susanne Grandl4, Martin Dierolf1,2, Klaus Achterhold1,2, Franz Pfeiffer1,2,4, and Julia Herzen1,2 — 1Chair of Biomedical Physics, Department of Physics, TU Munich, Germany — 2Munich School of BioEngineering, TU Munich, Germany — 3Chair of Experimental Physics IV, TU Dortmund, Germany — 4Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, TU Munich, Germany
Although the introduction of screening mammography has reduced the mortality rate of breast cancer, many women still undergo unnecessary subsequent examinations due to inconclusive diagnoses. In breast imaging, the low soft-tissue contrast of conventional attenuation-based images can be improved by phase-contrast imaging. Here, the diagnostic performance of multimodal grating-based mammography on four freshly dissected breast specimens and one mammographic accreditation phantom was evaluated at a compact synchrotron source. We found enhanced diagnostic information in monochromatic grating-based phase-contrast and dark-field images while the applied dose was lower or equal to the clinical dose. Microcalcifications could be identified equally well at significantly reduced dose in the monochromatic images. The results indicate that compact synchrotron sources can bring benefits to clinical imaging for mammography.