Rostock 2019 – scientific programme
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MO: Fachverband Molekülphysik
MO 24: Large and Reactive Systems
MO 24.7: Talk
Friday, March 15, 2019, 12:00–12:15, S HS 002 Biologie
Can you hear an axon growing? — •Frederic Folz1, Lukas Wettmann1, Giovanna Morigi1, and Karsten Kruse2 — 1Theoretische Physik, Universität des Saarlandes, 66041 Saarbrücken, Germany — 2NCCR Chemical Biology, Departments of Biochemistry and Theoretical Physics, University of Geneva, 1211 Geneva, Switzerland
Axons are linear structures of nerve cells that can range from a few tens of micrometers up to meters in length. In addition to external cues, the length of an axon is also regulated by unknown internal mechanisms. Molecular motors have been suggested to generate oscillations with an axon-length dependent frequency that could be used to measure an axon's extension. Here, we present a mechanism for determining the axon length that couples the mechanical properties of an axon to the spectral decomposition of the oscillatory signal.