Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe
Q: Fachverband Quantenoptik und Photonik
Q 24: Poster: Quantum Optics and Photonics I
Q 24.11: Poster
Dienstag, 12. März 2019, 16:30–18:30, S Fobau Physik
Superresolution via 3D structured illumination intensity correlation microscopy — •Anton Classen1,2, Joachim von Zanthier1,2, and Girish S. Agarwal3 — 1Institut für Optik, Information und Photonik und — 2Erlangen Graduate School in Advanced Optical Technologies (SAOT), Universität Erlangen-Nürnberg, 91052 Erlangen — 3Texas A&M University, College Station, TX 77843, USA
Intensity correlation microscopy (ICM), which is prominently known through antibunching microscopy or super-resolution optical fluctuation imaging (SOFI) [1,2], provides superresolution through a correlation analysis of antibunching of independent quantum emitters [1] or temporal fluctuations of blinking fluorophores [2]. For correlation order m the PSF is effectively taken to the mth power, and directly shrunk by the factor √m. Combined with deconvolution a close to linear resolution improvement of factor m can be obtained. Yet, analysis of high correlation orders is challenging, what limits the achievable resolutions. Here we propose to use three dimensional structured illumination [3] along with ICM to obtain an enhanced scaling of up to m+m=2m [4]. Hence, resolutions far below the diffraction limit in full 3D imaging can potentially be achieved already with low correlation orders. Since ICM operates in the linear regime our approach may be particularly promising for enhancing the resolution in biological imaging at low illumination levels. [1] O. Schwartz et al., PRA 85, 033812 (2012); [2] T. Dertinger et al., PNAS 106, 22287 (2009); [3] M. G. L. Gustafsson et al., J. Micr. 198, 82 (2000), Biophys. J. 94, 4957 (2008); [4] A. Classen et al., Optica 4, 580 (2017), Opt. Exress 26, 27492 (2018)