Dresden 2020 – scientific programme
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BP: Fachverband Biologische Physik
BP 10: Poster III
BP 10.31: Poster
Monday, March 16, 2020, 17:30–19:30, P2/3OG
Nonlinear response of noisy neurons with spike-triggered adaptation — •Christoph H. Egerland1 and Benjamin Lindner1,2 — 1Humboldt-Universität zu Berlin, Berlin, Germany — 2Bernstein Center for Computational Neuroscience, Berlin, Germany
A basic question in neuroscience is how a noisy neuron responds to an external stimulus signal. For weak stimuli, typically only the linear response in the firing rate has been considered. More recently, the weakly nonlinear response to periodic stimulu has been in the focus, demonstrating pronounced effects in particular for stimuli consisting of two harmonic signals [1]. Here we extend this analysis to neurons with adaptation currents because it is unclear how these slow currents that are present in many cells will affect the weakly nonlinear response. We show results obtained from simulations and compare them to analytically obtained expressions in the appropriate limits.
[1] Voronenko & Lindner New J. Phys. 19, 033038 (2017)