Dresden 2020 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 35: Bioimaging and Biospectroscopy II
BP 35.8: Vortrag
Donnerstag, 19. März 2020, 17:15–17:30, HÜL 386
Thermal non-equilibrium drives concentration, salt and pH gradients — •Thomas Matreux, Dieter Braun, and Christof B. Mast — Systems Biophysics, Ludwig-Maximilians-Universität, München, Deutschland
The first steps in the emergence of life on Earth occurred on rocks and their constituent phases with a feedstock of simple molecules. Our aim is to combine this scenario with thermal non-equilibrium and bring together geomaterials, chemistry and microfluidics in a realistic environment.
The reaction chambers are sandwiched between highly heat conducting sapphire plates ensuring complete thermal control including possible thermal gradients. Microfluidic structures are made from FEP, which lets us focus on the interactions between the molecules. Ions leached from prebiotically plausible mineral samples are selectively accumulated by thermal gradients and permit enzymatic activity. Thermal non-equilibrium boundary conditions drive concentration gradients, enabling chemical reactions and generating and controlling pH gradients in a plausible prebiotic scenario. Local gradients driven by heat fluxes will offer unique opportunities to enable molecular selection and evolution at the origins of life.