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BP: Fachverband Biologische Physik
BP 7: Biomaterials and Biopolymers (joint session BP/CPP)
BP 7.8: Vortrag
Montag, 16. März 2020, 17:15–17:30, ZEU 250
Characterization of microstructures obtained by the cryo-printing method for rapid microfluidic chip fabrication — •Sebastian Ronneberger, Ales Charvat, Claudia Hackl, Christian Elsner, and Bernd Abel — Leibniz Institute of Surface Engineering (IOM), Leipzig, Germany
Cryo-printing is a non-conventional rapid prototyping method for microfluidic devices in which liquid state (aqueous) micro-droplets are deposited onto a cooled substrate surface like glass or silicon which immediately undergo transition to the frozen solid state. By a controlled motion between the substrate surface and the microdrop printing head microstructures of ice can be scribed. After coverage of the microstructures with an UV-cured polymer coating thawing releases an *inverse imprint* in the covering coating which is still bonded to the substrate forming a microfluidic device. The talk presents off-line characterization methods for the topological analysis of cryo-printed ice microstructures by using datasets obtained from a laser-scanning profilometer. The datasets were automatically analyzed applying self-coded Python3 scripts to obtain channel parameters such as channel widths and channel depths at different positions. Analysis of crafted microchannels shows that this method can be used for optimizing the printing parameters which have an influence on the shape of the created microchannel structures. Furthermore, the reproducibility of the printing process was assessed. This might enable cryo-printing of microfluidic channels with variable and customized channel parameters which could be applied in advanced cryo-printed microfluidic chips.