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MA: Fachverband Magnetismus

MA 57: Posters Magnetism II

MA 57.30: Poster

Donnerstag, 19. März 2020, 15:00–18:00, P3

An Efficient Magnetothermal Actuation Setup for Biomedical Applications — •Amirarsalan Asharion and Cornelia Monzel — Experimental Medical Physics, Heinrich-Heine University Düsseldorf, 40225 Düsseldorf, Germany

Magnetic hyperthermia is a promising approach for biomedical applications. Here, magnetic nanoparticles are used as heating agents to increase the temperature in the nanometer vicinity of the particle surface with minimal side-effects on the surrounding tissue. The heat dissipation arises from energy delivered to the nanoparticles in the form of an alternating magnetic field. While clinical applications are in their nascent state, live-observations of single cells could be a huge asset to improve our understanding of the heating effect on cells or on individual heat-sensitive molecules. In this work, a magnetic hyperthermia setup with a small form factor is implemented under the microscope. The setup provides an alternating magnetic field with magnetic flux densities in the range of 10-100 mT, with a frequency of 10-500 kHz, applied to a volume of 1 cm^3. We discuss the different components of this setup, the electromagnet and electric circuit, as well as essential improvements to reduce power loss.