Hannover 2020 – scientific programme
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A: Fachverband Atomphysik
A 13: Clusters II (joint session MO/A)
A 13.3: Talk
Tuesday, March 10, 2020, 14:30–14:45, f142
Cryogenically Cooled Beams of Bio-Nanoparticles — •Lena Worbs1,2, Jannik Lübke1,2,3, Armando Estillore1, Amit K. Samanta1, and Jochen Küpper1,2,3 — 1Center for Free-Electron Laser Science, Deutsches-Elektronen Synchrotron DESY, Hamburg — 2Fachbereich Physik, Universität Hamburg — 3Center for Ultrafast Imaging, Hamburg
Coherent diffractive imaging at free-electron lasers promises to allow the reconstruction of the three-dimensional molecular structures of isolated particles at atomic resolution [1]. However, because of the typically low signal to noice ratio, this requires the collection of a large amount of diffraction patterns. Since every intercepted particle is destroyed by the intense x-ray pulse, a new and preferably identical sample particle has to be delivered into every pulse.
We present novel approaches for the production of high density particle beams of shock-frozen bio-nanoparticles using a cryogenic buffer-gas cooling technique [2]. We have also developed a numerical simulation infrastructure that allows quantitative simulation of isolated particle trajectories inside the buffer-gas cell. The cryogenically-cooled nanoparticle beams are characterized using laboratory-based light-scattering [3]. To further improve the resulting particle beam, an aerodynamic lens is implemented to increase its density.
[1] M. M. Seibert, et al., Nature 470, 78 (2011).
[2] A. K. Samanta, et al., arXiv:1910.12606 [physics.bio-ph]
[3] L. Worbs, et al., Opt. Expr., arXiv:1909.08922 [physics.optics]