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BP: Fachverband Biologische Physik
BP 24: Poster B: Active Biological Matter, Cell Mechanics, Systems Biology, Computational Biophysics, etc.
BP 24.22: Poster
Dienstag, 23. März 2021, 16:00–18:30, BPp
Influence of NaCl on Neuronal Membranes — •Sebastian Jaksch1, Alexandros Koutsioubas1, Piotr Zolnierczuk1, Olaf Holderer1, Henrich Frielinghaus1, Stephan Förster1, and Peter Müller-Buschbaum2 — 1Jülich Centre for Neutron Science (JCNS), Garching (Germany), Jülich (Germany) and Oak Ridge TN (USA) — 2Lehrstuhl für funktionelle Materialien, Physik-Department, Technische Universität München (Germany)
We previously investigated the structure and the dynamic behavior of L-α-phosphatidylcholine (SoyPC) phospholipid membranes, [1,2] by means of GISANS and GINSES and established a multi-lamellar structure as well as a surface mode, attributed to transient waves in the membranes. Extending those measurements to include various NaCl concentrations within the membrane we could identify two main features:[3] (1) The thickening of the membrane layers as reported by SAXS measurements is due to an enriched ion layer close to the head group of the phospholipid membranes, and not, as for hydrophobic molecules an actual swelling of the membrane. (2) The in-plane dynamics of the membranes is enhanced by the addition of NaCl, while retaining the previously reported surface mode. Those features can play an important role in the understanding of membrane functions, such as the formation of ion channels, and thus their biological function on a fundamental level. [1] S. Jaksch, et al, Phys. Rev. E 91(2), 2015, 022716. [2] S. Jaksch, et al, Scientific Reports 7(1), 2017, 4417. [3] S. Jaksch, et al, Influence of NaCl on the structure and dynamics of phospholipid layers, submitted.