BPCPPDYSOE21 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 24: Poster B: Active Biological Matter, Cell Mechanics, Systems Biology, Computational Biophysics, etc.

BP 24.33: Poster

Dienstag, 23. März 2021, 16:00–18:30, BPp

Intermediate scattering function in multi-channel dynamics: from model systems to particle-tracking data in live cells — •Cai Dieball¹, Adal Sabri², Xinran Xu³, Diego Krapf^3,4, Matthias Weiss², and Aljaz Godec¹ — ¹Mathematical bioPhysics Group, Max Planck Institute for Biophysical Chemistry, 37077 Göttingen, Germany — ²Experimental Physics I, University of Bayreuth, 95440 Bayreuth, Germany — ³Department of Electrical and Computer Engineering, Colorado State University, Fort Collins, Colorado 80523, USA — ⁴School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado 80523, USA

Several experimental techniques probe collective observables related to the intermediate scattering function, i.e. the expectation value of the Fourier-transformed displacement vectors of the system's particles. These techniques include neutron, X-ray and dynamic light scattering, neutron spin echo and Fourier imaging correlation spectroscopy, and differential dynamic microscopy. Intermediate scattering functions provide useful, complementary information even when applied to experiments that are able to track the motion of individual particles. In our work we analyze the intermediate scattering function in systems with "multi-channel" dynamics, i.e. dynamics stochastically switching between different modes of motion. We first inspect scattering fingerprints in simple model systems with two-channel dynamics. We then analyze trajectories from particle-tracking experiments in the cytoplasm of mammalian cells, and confirm that these display characteristics of anomalous, two-channel fractional Brownian motion.