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DY: Fachverband Dynamik und Statistische Physik
DY 25: Nonlinear Dynamics 2 - organized by Azam Gholami (Göttingen)
DY 25.4: Talk
Tuesday, March 23, 2021, 12:00–12:20, DYc
Understanding the origin of line defects in heart tissue. — •Marcel Hörning1, Alessandro Loppini2, Alessio Gizzi2, Flavio H Fenton3, and Simonetta Filippi2 — 1Institute of Biomaterials and Biomolecular Systems, University of Stuttgart, Stuttgart, Germany — 2University Campus Bio-Medico of Rome, Rome, Italy — 3School of Physics, Georgia Institute of Technology, Atlanta, Georgia, USA
Spatiotemporal patterns are observed in a wide range of excitable systems. They have important and diverse regulatory functions. In the heart, excitable waves can form complex oscillatory and chaotic patterns even at an abnormally higher frequency than normal heart beats, which increase the risk of fatal heart conditions by inhibiting normal blood circulation. Previous studies suggested that the occurrence of line defects in alternans play a critical role in the stabilizion of those undesirable patterns. However, this nonlinear phenomenon is still poorly understood. It remains to be elucidated, how nodal lines form, what their origin is, and how they stabilise. Here we show new insights in the stability of those by observing and analysing nodal line dynamics in spiral waves (in-vitro) and entrained high-frequency waves (ex-vivo).