SAMOP 2021 – scientific programme
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MO: Fachverband Molekülphysik
MO 7: Poster 1
MO 7.19: Poster
Thursday, September 23, 2021, 17:30–19:30, P
Focused beams of small (bio-)nanoparticles from aerodynamic lens injectors — •Lena Worbs1,2, Jannik Lübke1,2,3, Amit K. Samanta1, and Jochen Küpper1,2,3 — 1Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Hamburg — 2Department of Physics, Universität Hamburg — 3Center for Ultrafast Imaging, Universität Hamburg
Determining structure and observing dynamics from isolated proteins and nanoparticles using x-ray diffractive single-particle imaging (SPI) requires sample-delivery and injection methods that provide one single particle per x-ray pulse in the interaction region. Aerodynamic-lens-stack (ALS) injectors have been used to deliver collimated and focused particle-beams for such experiments on larger nanoparticles (∼50-100 nm) [1]. We extended the use and detection of particle beams toward smaller nanoparticles and present simulations and experiments on the performance of ALS injectors for 25 nm polystyrene spheres. This highlights the use of ALS injectors for small bio-nanoparticles. In addition, we present techniques to separate particles [2] according to charge caused by the aerosolization method employed. This paves the way toward pure beams of identical particles for SPI experiments.
[1] K. Ayyer, et al.; Optica 8(1), 15-23 (2021)
[2] Y.-P. Chang, et al.; Int. Rev. Phys. Chem. 34, 557-590 (2015)