Heidelberg 2022 – wissenschaftliches Programm
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ST: Fachverband Strahlen- und Medizinphysik
ST 1: Radiation therapy I
ST 1.6: Vortrag
Montag, 21. März 2022, 15:15–15:30, ST-H4
Proton field verification by implant activation — •Claus Maximilian Bäcker1,2,3, Christian Bäumer1,2,3, Walter Jentzen5, Sandra Laura Kazek5, Kevin Kröninger1, Fleur Spiecker1, Nico Verbeek2,3, Jens Weingarten1, Jörg Wulff2,3, and Beate Timmermann2,3,4,6 — 1TU Dortmund University, Department of Physics, D-44221 Dortmund — 2West German Proton Therapy Centre Essen, D-45122 Essen — 3University Hospital Essen, West German Cancer Center, D-45122 Essen — 4University Hospital Essen, Department for Particle Therapy, D-45122 Essen — 5University Hospital Essen, Clinic for Nuclear Medicine, D-45122 Essen — 6University Duisburg/Essen, Faculty of Medicine, D-45147 Essen
The delivered dose in particle therapy is sensitive to the correctly predicted range. Uncertainties arise e.g. from estimation of tissue stopping powers. In order to identify range uncertainties of the treatment fields, multiple techniques have been developed in the past. However, these techniques come with several limitations for the clinical applicability. In this study, the potential use of implant activation for field verification is investigated. Therefore, a method validation is performed focusing on the activation of titanium implants during proton therapy treatments and subsequent PET imaging. The parameters delivered dose and variations in the beam range are investigated to estimate the detectability of these changes during fractional treatment. While first pre-clinical studies demonstrated the general potential of implant activation for range verification, the current limitations and necessary developments in PET imaging will be presented in this talk.