Heidelberg 2022 – scientific programme
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ST: Fachverband Strahlen- und Medizinphysik
ST 8: Radiation therapy II
ST 8.4: Talk
Thursday, March 24, 2022, 11:45–12:00, ST-H4
Monte Carlo simulations of a combination of brachytherapy and external X-ray irradiation for the treatment of intraocular tumors — •Michelle Stroth1, Henning Manke1, Justine Gemmecke1, Saskia Müller1, Dirk Flühs2, and Bernhard Spaan1 — 1Experimental Physics 5, TU Dortmund — 2Department of Radiotherapy, University hospital Essen
Brachytherapy with ruthenium-106 eye plaques is a standard modality for the treatment of intraocular tumors. In order to ensure a sufficient tumor apex dose even in larger tumors without exceeding dose limits at neighboring organs at risk, the concept of combining eye plaque brachytherapy with an external beam from a precisely positioned X-ray tube is currently being investigated.
For this purpose, a generic eye model is created using the CAD software Fusion 360 and adapted to the data of real patient cases. The area of the exit window of the X-ray tube is created for various positions depending on the tumor apex, so that different directions of photon irradiation are simulated. A decomposition of the model into many sub-volumes and their implementation in a Monte Carlo simulation in Geant4 allows the analysis of local dose profiles and dose-volume-histograms in organs at risk and the tumor.
This presentation shows the setup of the simulation and first results of combining brachytherapy with external X-ray irradiation.