Regensburg 2022 – wissenschaftliches Programm
Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe
BP: Fachverband Biologische Physik
BP 12: Poster 2
BP 12.50: Poster
Dienstag, 6. September 2022, 17:30–19:30, P4
Study of the temporal stability of evaporated SLBs for technological applications — •Nancy Gomez-Vierling1, Marcelo A. Cisternas2, María José Retamal1, Nicolás Moraga1, Marco A. Soto-Arriaza3, Tomás P. Corrales4, Felix Kleemann5, and Ulrich G. Volkmann1 — 1Instituto de Física and CIEN-UC, P. Univ. Católica de Chile — 2Escuela de Ingeniería Industrial, Univ. de Valparaíso, Chile — 3Facultad de Química y Farmacia and CIEN-UC, P. Univ. Católica de Chile — 4Departamento de Física, UTFSM, Valparaíso, Chile — 5Departamento de Física, Technische Universität Clausthal, Clausthal, Germany.
Artificial membranes are models for biological systems. We introduce a dry two-step self-assembly method, first performing a high-vacuum evaporation of phospholipid molecules over silicon, followed by an annealing step in air. Our evaporated membranes show long-term stability and no restructuring after storage in air during at least fifteen months. This extreme stability of the Supported Lipid Bilayer (SLB) structures make this system interesting for technical applications in the field of functional biointerfaces, e.g., for fabrication of biosensors and membrane protein platforms, including cleanroom-compatible fabrication technology. It is expected that SLBs can help to gain insight into the lifetime of viral structures protected by a surrounding phospholipid bilayer adsorbed on static solid surfaces or on inhalable particulate material (PM), which contributes to the spread of the SARS-CoV-2 virus. Acknowledgment: FONDECYT grant numbers 1180939 (UGV), 1171047 (MS-A) and 1211901 (TPC).