Regensburg 2022 – scientific programme
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BP: Fachverband Biologische Physik
BP 12: Poster 2
BP 12.51: Poster
Tuesday, September 6, 2022, 17:30–19:30, P4
Measurements of topologies and Young moduli of DPPC films deposited from the gas phase onto silicon substrates at different temperatures — •Nicolás Moraga1, Gabriel Alfaro1, Nancy Gomez-Vierling1, Daniel Saavedra1, Marcelo A. Cisternas2, María José Retamal1, Marco A. Soto-Arriaza3, Tomás P. Corrales4, Felix Kleemann5, and Ulrich G. Volkmann1 — 1Instituto de Física and CIEN-UC, P. Univ. Católica de Chile — 2Escuela de Ingeniería Industrial, Univ. de Valparaíso, Chile — 3Facultad de Química y de Farmacia and CIEN-UC, P. Univ. Católica de Chile — 4Departamento de Física, UTFSM, Valparaíso, Chile — 5Departamento de Física, Technische Universität Clausthal, Clausthal, Germany.
Supported lipid bilayers (SLBs) are suited to gain insight into the physical behavior of cell membranes. In this work, DPPC deposition by Physical Vapor Deposition (PVD) is performed on silicon (100) substrates at different substrate temperatures and deposition rates. Our goal is finding growth parameters, to optimize coverage and homogeneity of the DPPC SLBs. We observe a modification of topologies and Young moduli and an optimization of the homogeneity for substrate temperatures between 310 and 315 K and deposition rates in the range of 0,78 to 0,93 Å/min. Homogeneous, planar biomimic phospholipid membranes avail protein insertion and an easier detection of ionic channels which will form in case of Gramicidin [Kelkar et. al, BBA 1768 (2007) 2011-25]. Acknowledgment: FONDECYT grant numbers 1180939 (UGV), 1171047 (MS-A) and 1211901 (TPC).