Regensburg 2022 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 3: Cell Mechanics 1
BP 3.7: Vortrag
Montag, 5. September 2022, 11:30–11:45, H15
Red blood cell shape transitions and dynamics in time-dependent capillary flow — •Katharina Graessel1, Steffen M. Recktenwald2, Felix M. Maurer2, Thomas John2, Christian Wagner2,3, and Stephan Gekle1 — 1Biofluid Simulation and Modeling, Theoretische Physik VI, University of Bayreuth — 2Dynamics of Fluids, Experimental Physics, Saarland University — 3Physics and Materials Science Research Unit, University of Luxembourg
Red blood cells in small microchannels flow in characteristic shapes, mainly symmetric croissants at the channel center and non-symmetric off-centered slippers. While these shapes have been studied for some time, not much is known about the transition dynamics between different states. Here, we use boundary-integral simulations together with microfluidic experiments in time-dependent flows to observe and understand red blood cell shape transitions. The transition from the croissant to the slipper shape happens much faster than the opposite transition. We find that the center of mass of slipper cells shows lateral oscillations due to the tank-treading movement of the RBC membrane. The oscillation frequency increases with the cell velocity and the viscosity of the surrounding fluid.