Regensburg 2022 – wissenschaftliches Programm

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MA: Fachverband Magnetismus

MA 35: Poster 2

MA 35.55: Poster

Donnerstag, 8. September 2022, 16:00–18:00, P4

An Efficient Magnetic Hyperthermia Setup for Controlled Nanoparticle Heating — •Daniel Kuckla, Julia-Sarita Brand, Vinzenz Jüttner, and Cornelia Monzel — Heinrich-Heine-Univerity,Düsseldorf,Germany

Magnetic hyperthermia is a promising approach to enable a remote and localized heating of magnetic nanoparticles (MNPs) with various applications in condensed matter or biomedical physics. The MNPs may be positioned precisely in space and act as hot spots by increasing the temperature in the nanometer vicinity of the particle while causing minimal effects on the macroscopic environment. The heat dissipation arises from energy delivered to the nanoparticle in the form of an alternating magnetic field with ∼100kHz frequency and 50mT magnetic flux density. A particular challenge is to realize an efficient magnetic hyperthermia setup and to image the localized heating. Here, we present such setup consisting of an electromagnet in a resonance circuit and exhibiting a small form factor to be implemented under a microscope. We provide a profound characterization of the different components of this setup - the electromagnet and electric circuit, essential improvements to reduce power loss arising from electromagnetic induction as well as strategies to directly record thermal changes. We demonstrate efficient heating/cooling cycles using well-defined MNP samples in suspension and create MNP lithographically structured substrates. Our setup may be used to create localized hot spots in condensed matter samples, to create thermofunctional switches or to study heat-sensitive molecules in biophysics, among other examples.