SAMOP 2023 – wissenschaftliches Programm
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Q: Fachverband Quantenoptik und Photonik
Q 4: Cold Molecules (joint session MO/Q)
Q 4.2: Vortrag
Montag, 6. März 2023, 11:15–11:30, F102
Cryo-cooled beams of “small” macromolecules — •Jingxuan He1,2,3, Lena Worbs1,2, Surya Kiran Peravali1,4, Armando D. Estillore1, Amit K. Samanta1,3, and Jochen Küpper1,2,3 — 1Center for Free-Electron Laser Science, Deutsches Elektronen-Synchrotron DESY, Hamburg, Germany — 2Department of Physics, Universität Hamburg, Germany — 3Center for Ultrafast Imaging, Universität Hamburg, Germany — 4Fakultät für Maschinenbau, Helmut-Schmidt-Universität,Germany
We have demonstrated the preparation of cold and controlled dense beams of nanoparticles and macromolecules designed for x-ray single-particle diffractive imaging (SPI). We exploit buffer-gas cell cooling and aerodynamic focusing techniques [1-2]. We are extending the cooling and control techniques developed for SPI to experimental investigations of ultrafast electron dynamics in complex biomolecules. We aim at disentangling charge and energy transfer following electronic excitation, which still has important open questions [3].
Here, we present our approach to prepare appropriate samples of cryogenically-cooled proteins to study these also biologically important elemantary processes, for instance, using photofragmentation mass spectrometry and velocity map imaging.
[1]A. K. Samanta, et al., Structural dynamics 7 , 024304 (2020)
[2]L. Worbs, et al., In preparation, (2022)
[3]H. Duan, et al., PNAS 114 , 8493 (2017)