SKM 2023 – scientific programme
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BP: Fachverband Biologische Physik
BP 11: Poster Session I
BP 11.67: Poster
Tuesday, March 28, 2023, 12:30–15:30, P1
Density fluctuation analysis of living matter — •Conrad Möckel1,2,3, Kyoohyun Kim1,2, Abin Biswas1,2,4, Simone Reber4, Vasily Zaburdaev1,2,5, and Jochen Guck1,2,3 — 1Max Planck Institute for the Science of Light, 91058 Erlangen, Germany — 2Max Planck Zentrum für Physik und Medizin, 91058 Erlangen, Germany — 3Department of Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany — 4IRI Life Sciences, Humboldt-Universität zu Berlin, 10115 Berlin, Germany — 5Department of Biology, Mathematics in Life Sciences, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany
The characterisation of the dynamical properties of living matter plays an important role in unraveling its complexity. Here we present the combination of quantitative phase imaging with differential dynamic microscopy in order to probe and evaluate its inherent density fluctuations. By employing theoretical models, this approach allows for the determination of the time- and length scale dependent viscoelastic properties of optically transparent systems as demonstrated for high speed supernatant (HSS) Xenopus laevis egg extract. We find that HSS exhibits distinct dynamics at two time scales which can be explained by diffusion in a diffusing potential.