SKM 2023 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 21: Bioimaging

BP 21.7: Hauptvortrag

Donnerstag, 30. März 2023, 11:15–11:45, BAR Schö

Visualizing the inner life of microbes — •Ulrike Endesfelder — Institute for Microbiology and Biotechnology, Bonn University, Germany

Microbes, as unicellular organisms, are crucial model systems for the study of cellular mechanisms and functions. With the advent of modern fluorescence microscopy techniques, we can now visualize the inner workings of microbes at the molecular level, e.g. the dynamics of single molecules and the molecular architecture of sub-cellular structures. By quantifying the molecular characteristics of microbes in vivo, we thus can create detailed, spatially and temporally resolved maps of their molecular makeup, allowing us to understand the dynamic heterogeneity and sub-populations at the sub-cellular level. In this talk, I will discuss the potential of single-molecule biophysical approaches for microbiology, using examples from our own research and outlining our future visions.