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BP: Fachverband Biologische Physik

BP 28: Poster Session II

BP 28.40: Poster

Thursday, March 30, 2023, 18:00–20:00, P2/EG

Coordination of information in Physarum polycephalum — •Kaspar Wachinger¹, Johnny Tong¹, Nico Schramma², Siyu Chen¹, and Karen Alim¹ — ¹School of Natural Sciences, Technical University of Munich, Germany — ²Faculty of Science, University of Amsterdam, The Netherlands

Physarum polycephalum is a network-structured, single-cell organism with thousands of nuclei that can sense and adapt to its environment. To understand how P. polyephalum maintains efficient gene expression, it is necessary to understand the coordinated intracellular transport of nuclei within its structure. Microinjecting several fluorescent dsDNA markers into the tubes of P. polyephalum allows in-vivo imaging of nuclei and their dynamics: Nuclei can either be trapped in the more solid wall cortex or follow the oscillatory cytoplasmic streaming. We investigate the flow-driven behaviours of nuclei in functionally different regions of P. polycephalum’s network and motivate a hypothesis of inter-nuclei communication far past the degradation distance of mRNA.