SKM 2023 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 9: Active Matter III (joint session BP/CPP/DY)

BP 9.11: Vortrag

Dienstag, 28. März 2023, 12:15–12:30, TOE 317

Two-potential model for molecular motors — •Sophie Klempahn and Helmut Schießel — Cluster of Excellence Physics of Life, Technical University of Dresden, Germany

Molecular motors are highly efficient biological machines, which drive systems away from equilibrium and realise key biological processes. For the description of the molecular motor action, discrete jump processes as well as energy barriers with height differences can be used. However, these models are based on symmetric conditions or unidirectional motion and therefore do not capture real biological systems with fuel gradients or where the motion is not unidirectional. To predict the effect of molecular motors on the density distribution of cargo particles in one dimension, we introduce a two potential model. This model represents the cargo particles as active particles, in which the binding of molecular motors to the cargo particle causes the active part of motion. Furthermore, we use two different energy landscapes for jumps to the left or right side, to include motors moving back- and forward, asymmetric environment or two different molecular motors acting on the same cargo particle in different directions. The solution of a master equation with different energy landscapes for jumps to the left and right side results in specific extremal points in the probability density of the cargo particles and shows a ratchet effect in case of periodic potentials.