SKM 2023 – scientific programme
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CPP: Fachverband Chemische Physik und Polymerphysik
CPP 35: Poster Session II
CPP 35.60: Poster
Wednesday, March 29, 2023, 11:00–13:00, P1
A thermo- and photoresponsive polymer for schizophrenic switching of amphiphilic self-assembled micelles — •Peiran Zhang1, René Steinbrecher2, André Laschewsky2,3, Peter Müller-Buschbaum4, and Christine M. Papadakis1 — 1Soft Matter Physics Group, TUM School of Natural Sciences, Technical University of Munich — 2Institute of Chemistry, University of Potsdam — 3Fraunhofer IAP, Potsdam-Golm — 4Chair for Functional Materials, TUM School of Natural Sciences, Technical University of Munich
Schizophrenic switching, namely the exchanging of hydrophilic and hydrophobic segment of an amphiphilic diblock copolymer, leads to self-assembly of micelles and inverse micelles, which can be used in the drug delivery application [1]. We aim to achieve such behavior by means of diblock copolymers composed of a thermo-responsive block with a fixed LCST (lower critical solution temperature) and a photo-responsive block with a tunable LCST, which is accomplished by cis-trans isomerization of the incorporated azobenzene group. As a first step, we use turbidimetry and dynamic light scattering (DLS) to investigate a homopolymer precursor with respect to the cloud point and the chain size in the cis- and trans-form of the azobenzene group, which is realized by 365 nm UV light and 470 nm blue light, respectively.
[1] C. M. Papadakis, P. Müller-Buschbaum, A. Laschewsky, Langmuir 2019, 35, 9660-9676.