SKM 2023 – wissenschaftliches Programm

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DY: Fachverband Dynamik und Statistische Physik

DY 45: Poster: Nonlinear Dynamics, Pattern Formation and Networks

DY 45.8: Poster

Donnerstag, 30. März 2023, 13:00–16:00, P1

Coupling short-range signaling and tissue mechanics for biological pattern formation — •Valèria Ribelles Pérez, Stephan Kremser, Mareike Bojer, Sabina Orazov, and Ulrich Gerland — Physics Department, Technical University of Munich

Pattern formation phenomena are ubiquitous in natural and synthetic multicellular systems. Both mechanical forces and biochemical interactions between cells play key roles in tissue dynamics. While much is known about these physical and biochemical processes separately, their interplay is still poorly understood. Here, we focus on short-range signaling between cells, modelled by cellular automata, coupled to a vertex model incorporating mechanical interactions, to investigate patterning principles during tissue homeostasis and growth. We test the modelling framework in the context of salt-and-pepper-like patterns that arise for instance in epithelial tissues.