SMuK 2023 – scientific programme

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ST: Fachverband Strahlen- und Medizinphysik

ST 9: Radiation Therapy

ST 9.1: Talk

Thursday, March 23, 2023, 15:50–16:05, ZEU/0146

A novel therapy concept for intraocular tumors — •Henning Manke¹, Michelle Stroth¹, Dirk Flühs², Bernhard Spaan¹, and Johannes Albrecht¹ — ¹TU Dortmund University, Dortmund, Germany — ²Department of Radiotherapy, Essen University Hospital, Germany

To investigate the suitability of a new therapy concept for intraocular tumors consisting of both brachy- and radiotherapy a new phantom was developed and tested. Tumors with a height up to 7 mm are mostly treated with Ruthenium-106 plaques. Due to the steep dose gradient, tumors with a higher apex are irradiated insufficiently. A therapy modality for tumors that big is to use Iodine-125 plaques, but due to their isotropic gamma radiation healthy tissue is partly irradiated and damaged. The new concept consists of simultaneous therapy with Ruthenium-106 plaques and X-ray. Both the tumor base and apex can be irradiated sufficiently while sparing healthy tissue. The plaque may serve as an absorber for the X-rays.

A new phantom was constructed from the material Plastic Water Low Range to measure dose profiles of X-rays in front and behind a Ruthenium-106 plaque. Three different detectors can be used in the phantom to measure dose profiles: a soft X-ray chamber, radiochromic films and self-made scintillation detectors. Measurements have been performed with a X-ray therapy unit type T-105 distributed by BEBIG Medical GmbH.

This talk presents the first results which show an appropriate application of the combined therapy.