Berlin 2024 – wissenschaftliches Programm

Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe

BP: Fachverband Biologische Physik

BP 20: Poster IIIa

BP 20.1: Poster

Mittwoch, 20. März 2024, 11:00–14:30, Poster B

Influence of Environmental Inhomogeneity on Active Particle Dynamics in Obstacle Parks: A Numerical Study — •Zeinab Sadjadi¹ and Heiko Rieger^1,2 — ¹Department of Theoretical Physics & Center for Biophysics, Saarland University, 66123 Saarbrücken, Germany — ²Leibniz Institute for New Materials INM, 66123 Saarbrücken, Germany

Biological microorganisms have the ability to detect external fields and environmental signals, and they can adjust their dynamics accordingly. The redirected motion in response to a gradient of a stimulus, called taxis, is a vital navigation mechanism in many biological systems. Our focus lies on topotaxis, the ability of particles to sense the geometrical and topographical features of their surroundings. We numerically study the dynamic behavior of active particles moving in pillar parks. First, by introducing a disorder in the diameter size as well as the position of pillars, we investigate the influence of environmental inhomogeneity on particle dynamics. we also demonstrate how imposing a gradient in the disorder in geometrical characteristics could bias the direction of active agents and induce a topotaxis in the pillar park. Our results are of technological importance for design of efficient taxis devices.

Keywords: Cell migration; Topotaxis; Active particles; Diffusion; obstacle park