Berlin 2024 – scientific programme

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BP: Fachverband Biologische Physik

BP 20: Poster IIIa

BP 20.24: Poster

Wednesday, March 20, 2024, 11:00–14:30, Poster B

Spherical harmonics and the morphology of red blood cells — •Thomas John, Felix Maurer, and Christian Wagner — Campus E26, 66123 Saarbrücken

Red blood cells are highly flexible and, at rest (without flow), exhibit a biconcave shape. Under flow conditions, altered environmental parameters, or due to diseases, this shape can deviate significantly from its resting state. Using 3D images obtained through confocal microscopy, we demonstrate how the shape, and thus the surface, can be represented as an expansion in spherical harmonics. This parameterization is rotationally invariant and can be utilized to distinguish between various cell shapes. This, in turn, can be done conventionally or through AI-based methods.

Keywords: red blood cell; cell shape; spherical harmonics