Berlin 2024 – scientific programme
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BP: Fachverband Biologische Physik
BP 28: Cytoskeleton
BP 28.4: Invited Talk
Thursday, March 21, 2024, 10:30–11:00, H 2032
Quantifying the actin cortex of cells in different states — •Franziska Lautenschläger1, Daniel Flormann1, Christoph Anton1, and Rhoda Hawkins2 — 1Saarland University — 2AIMS Ghana, Accra
The actin cortex defines the shape of cells and is involved in a plethora of cellular functions. We aim to describe, predict and alter changes in cellular states by alterations of the actin cortex. I will show two examples of changes of a cellular states and their corresponding cortex alterations: An adhered cell compared with a suspended cell and a single cell compared with a cell in a monolayer. The parameters we chose to describe the actin cortex are the thickness, the mesh size, the bundling as well as the stiffness of the actin cortex. We compare our data of the actin cortex in cells with earlier theoretical and in vitro work and test theoretical predictions.
Keywords: Actin; Cortex; cell mechanics; mesh size