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BP: Fachverband Biologische Physik

BP 35: Active Matter V (joint session BP/DY)

BP 35.1: Talk

Friday, March 22, 2024, 09:30–09:45, H 1028

Noise reduction with droplets of many components — •Tyler Harmon — Leibniz Institute for Polymer Research, Dresden, Germany

Noise control is critical for cell homeostasis and decision making. We previously showed that phase separation could be used to robustly reduce noise in phase separating systems. Others have suggested that noise buffering has the strongest suppression of noise parallel to the coexistence tie lines. They proposed that correlations from features such as coupled transcription could align the noise with the tie lines, significantly reducing the noise. Here we show how the kinetics associated with phase diagrams naturally aligns the noise to the tie lines. This helps optimize the noise reduction in systems with many components.

Keywords: Biomolecular condensates; Noise reduction; Droplets