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Berlin 2024 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 4: Computational Biophysics I

BP 4.3: Vortrag

Montag, 18. März 2024, 15:30–15:45, H 0112

Modeling and simulation of red blood cells aggregation in cardiovascular networks — •Fouzia Imharken1,2, Chaouqi Misbah1, and Hamid Ez-zahraouy21Interdisciplinary Laboratory of Physics (LIPhy)-UGA-Grenoble- French — 2Laboratory of Condensed Matter and Interdisciplinary Sciences-Mohamed 5 University-Morocco

Cardiovascular dysfunctions due to undesirable adhesion among blood elements (like red blood cells-RBCs) are the main causes of mortality in the world. In our study, we intend to develop simple models to better understand the perfusion of blood in microcirculation by considering a complex geometry under several conditions (shear, confinement, pressure, etc.) in the presence of adhesion among RBCs using an immersed boundary-lattice Boltzmann method. Our primary results show that the aggregation of RBCs and their mechanical properties has a strong impact on their distribution in the network. For stiff RBCs (due to a disease) a weak adhesion leads to super diffusion instead of ballistic transport, as compared to the case without adhesion.

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