Berlin 2024 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 4: Computational Biophysics I
BP 4.3: Vortrag
Montag, 18. März 2024, 15:30–15:45, H 0112
Modeling and simulation of red blood cells aggregation in cardiovascular networks — •Fouzia Imharken1,2, Chaouqi Misbah1, and Hamid Ez-zahraouy2 — 1Interdisciplinary Laboratory of Physics (LIPhy)-UGA-Grenoble- French — 2Laboratory of Condensed Matter and Interdisciplinary Sciences-Mohamed 5 University-Morocco
Cardiovascular dysfunctions due to undesirable adhesion among blood elements (like red blood cells-RBCs) are the main causes of mortality in the world. In our study, we intend to develop simple models to better understand the perfusion of blood in microcirculation by considering a complex geometry under several conditions (shear, confinement, pressure, etc.) in the presence of adhesion among RBCs using an immersed boundary-lattice Boltzmann method. Our primary results show that the aggregation of RBCs and their mechanical properties has a strong impact on their distribution in the network. For stiff RBCs (due to a disease) a weak adhesion leads to super diffusion instead of ballistic transport, as compared to the case without adhesion.
Keywords: red blood; aggregation; transport; immersed boundary-lattice boltzmann method; microcirculation