Berlin 2024 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 5: Tissue Mechanics I
BP 5.8: Vortrag
Montag, 18. März 2024, 17:15–17:30, H 0110
Wrinkling instability in unsupported epithelial sheets — •Urska Andrensek1,2, Primoz Ziherl1,2, and Matej Krajnc1 — 1Jozef Stefan Institute, Ljubljana, Slovenia — 2Faculty of Mathematics and Physics, University of Ljubljana, Slovenia
We investigate the elasticity of an unsupported epithelial monolayer and we discover that unlike a thin solid plate, which wrinkles if geometrically incompatible with the underlying substrate, the epithelium may do so even in absence of the substrate. From a cell-based model, we derive an exact elasticity theory and discover wrinkling driven by the differential apico-basal surface tension. Our theory is mapped onto that for supported plates by introducing a phantom substrate whose stiffness is finite beyond a critical differential tension. This suggests a new mechanism for an autonomous control of tissues over the length scale of their surface patterns.
Keywords: Epithelia; Wrinkling instability; Surface tension; Vertex model