Berlin 2024 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 7: Active Fluids and Microswimmers (joint session DY/BP/CPP)
BP 7.12: Vortrag
Montag, 18. März 2024, 18:15–18:30, BH-N 243
Opto-fluidic dynamic patterning of microparticles — •Elena Erben1, Weida Liao2, Antonio Minopoli3, Nicola Maghelli4, Eric Lauga2, and Moritz Kreysing1 — 1IBCS-BIP, KIT, Karlsruhe, Germany — 2DAMTP, University of Cambridge, UK — 3University of Pisa, Pisa, Itlay — 4Fondazione Human Technopole, Milano, Italy
Techniques for the precise manipulation of microscopic objects bear great potential for application in a wide range of fields, from basic biological research to microfabrication. Our method uses rapid scanning of an infrared laser beam to optically generate thermoviscous flows [1] within a sample. Combined with closed-loop control this enables the automatic positioning of a single microparticle, with a precision of up to 24 nm [2]. Our approach can be multiplexed to manipulate up to 15 particles in a parallel and dynamic fashion. Furthermore, we have found that the positioning of multiple particles can be greatly accelerated by exploiting the complex flow patterns that result from the time-sharing of different laser scan paths. We plan to combine our approach with a full analytical model of the flows [3], which we expect will further increase the precision and speed of this manipulation method, facilitating its translation to applications in the life sciences and beyond.
[1] Weinert et al. Phys. Rev. Lett. 2008; [2] Erben et al. Opt. Express 2021; [3] Liao et al. Phys. Rev. Fluids 2023.
Keywords: Micromanipulation; Microfluidics; Optofluidics; Microscopy; Method