Berlin 2024 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 8: Poster Session Ia

BP 8.19: Poster

Montag, 18. März 2024, 18:00–20:30, Poster C

Exploring Cell Shapes and Dynamics Through Discrete Differential Geometry — •Mauricio Rojas-Vega, Andela Šarić, and Christopher Wojtan — Institute of Science and Technology, Klosterneuburg, Austria

Our study utilizes the Canham-Helfrich bending energy model to validate anticipated cellular phenomena within membrane structures, identifying three primary equilibrium shapes. Introducing an external cargo attracted to the membrane confirms established interactions, resulting in observed budding and wrapping. These findings solidify our model's robustness in encapsulating known cellular behaviors.

Additionally, our research explores controlled membrane manipulations, enhancing the model's representation of fluid-like behavior. Future work aims to incorporate non-reciprocal interactions for exploring non-equilibrium cell shapes and validating the inside-out model.

This research consolidates understanding of established cellular interactions, offering avenues to explore non-equilibrium cellular phenomena, thereby advancing our comprehension of cellular dynamics.

Keywords: Membranes; Shape; Simulations