Berlin 2024 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 9: Poster Session Ib

BP 9.2: Poster

Montag, 18. März 2024, 18:00–20:30, Poster D

An analytical theory of the influence of a cell nucleus on cell deformation — •Clara Gremmelspacher and Stephan Gekle — Universität Bayreuth

We develop an analytical theory to investigate the influence of a nucleus on cell deformation under mechanical load. To do this, we use linear elasticity theory and compare the deformation of homogeneous and heterogeneous cells under different boundary conditions. From these calculations we aim at deriving effective elasticity moduli of these shell-nucleus systems. Our work is intended to give a theoretical background to the often used practice of simplifying cells with their complex internal structure as homogeneous cells in numerical simulations and experimental data analysis.

Keywords: analytical theory; effective elasticity moduli; shell-nucleus systems