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DY: Fachverband Dynamik und Statistische Physik
DY 20: Statistical Physics of Biological Systems I (joint session DY/BP)
DY 20.6: Talk
Tuesday, March 19, 2024, 11:00–11:15, BH-N 334
Single particle analysis of sorbing tracers — •Timo Doerries1, Aleksei Chechkin1,2,3, and Ralf Metzler1,4 — 1Institute of Physics & Astronomy, University of Potsdam, 14476 Potsdam, Germany — 2Faculty of Pure and Applied Mathematics, Hugo Steinhaus Center, Wrocław University of Science and Technology, Wyspianskiego 27, 50-370 Wrocław, Poland — 3Akhizer Institute for Theoretical Physics National Science Center “Kharkiv Institute of Physics and Technology”, 61108 Kharkiv, Ukraine — 4Asia Pacific Center for Theoretical Physics, Pohang 37673, Republic of Korea
Based on a simple switching diffusion process we describe tau proteins changing between a mobile (diffusive) and an immobile state, leading to strong non-Gaussian displacements. For long but finite observation times the time averaged mean squared displacements have a significant spread, of which we obtain the exact distribution. This behaviour is similar to the well known continuous time random walk, which has instantaneous jumps in contrast to our model. We discuss the role of the non-zero mobile duration in our model compared to the instantaneous jumps in the continuous time random walk.
Keywords: tau protein; mobile/immobile model; single particle; non-ergodicity