Berlin 2024 – wissenschaftliches Programm

Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe

MA: Fachverband Magnetismus

MA 13: Micro- and Nanostructured Magnetic Materials

MA 13.6: Vortrag

Montag, 18. März 2024, 16:15–16:30, EB 407

Exploring Sustainable Approaches for the Synthesis of Na β-type Hexagonal Ferrite Magnetic Nanoparticles and Their Application in the Electrochemical Detection of Cefixime — •Sajjad Hussain — Centre of Excellence in Solid State Physics, University of the Punjab, Lahore, Pakistan

The quantitative study of antibiotics is significant due to their extensive application in treating many diseases worldwide. Cefixime (Cfx) is a third-generation cephalosporin medicine used as an antibacterial. In the current project, using a ginger root extract, the sol-gel green methodology was used for sodium β-type hexagonal ferrite nanoparticles (NaFe11O17-NPs). The NaFe11O17-NPs were subjected to analytical characterization using X-ray diffraction (XRD), atomic force microscopy (AFM), field emission scanning electron microscopy (FE-SEM), X-ray photoelectron spectroscopy (XPS), and vibrating sample magnetometer (VSM) analysis. The characterization confirmed the prepared material's crystalline behaviour, surface morphology, particle size, surface area, and magnetic nature. The drop-casting method was used for an efficient electrochemical sensor by modifying a gold electrode (AuE) with sodium β-type hexagonal ferrite nanoparticles NaFe11O17-NPs/AuE to assist the sensitive and selective quantification of Cfx. The fabricated electrochemical method achieved a notably low detection limit of 14 nM. The developed sensor was applied successfully to quantitatively determine Cfx in clinical samples and pharmaceutical preparations with excellent recoveries from 95.20 to 102.48 %.

Keywords: Sol-gel green synthesis; NaFe11O17 NPs; Structural properties; Magnetic properties; Electrochemical sensor of Cefixime