Gießen 2024 – scientific programme

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HK: Fachverband Physik der Hadronen und Kerne

HK 72: Poster

HK 72.26: Poster

Thursday, March 14, 2024, 17:15–18:45, HBR 14: Foyer

Quasi-real-time range Monitoring in hadron therapy using positron emitters of carbon and oxygen — •Sivaji Purushothaman for the BARB- and Super-FRS Experiment collaboration — GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany

A fast and reliable range monitoring method is required to fully exploit the high linear energy transfer (LET) provided by therapeutic ion beams such as carbon and oxygen while minimizing damage to healthy tissue due to range uncertainties. Quasi-real-time range monitoring, utilizing in-beam positron emission tomography (PET) with therapeutic beams of positron-emitters of carbon and oxygen, proves to be a promising approach. An experimental comparative study of therapeutically relevant positron emitters of carbon and oxygen within this context was performed at the fragment-separator facility (FRS) as part of the BARB (Biomedical Applications of Radioactive Beams) project at GSI Helmholtzzentrum für Schwerionenforschung GmbH, Germany. The experimental results and the figure of merit metric developed for the qualitative comparison of the studied isotopes will be presented.

This work is supported by European Research Council (ERC) Advanced Grant 883425 (BARB) to Marco Durante. The measurements were performed within the Super-FRS Experiment Collaboration (Experiment No. S533 by S. Purushothaman et al.) at GSI in the framework of the FAIR Phase-0 experimental program.

Keywords: Hadron therapy; Quasi-real-time range monitoring; Positron emitters; Positron emission tomography (PET)